Conference schedule
Tuesday, September 3
17:00 Opening of the conference:
18.00-19.00 Opening lecture: Susan P. C. Cole, Division of Cancer Biology & Genetics, Queen's University Cancer Research Institute, Kingston, ON: Polymorphisms in the MRP (ABCC) Transporters: How important are they?
Wednesday, September 4 morning session
9.00-9.40 Dietrich Keppler, German Cancer Research Center (DKFZ), Heidelberg: Drug and conjugate efflux pumps of the ABCC subfamily: MRP2, MRP3 and MRP4
9.40-10.20 Gabriele Jedlitschky, Center of Drug Absorption and Transport, University of Greifswald: Role of multidrug transporters in cell signalling: physiological functions and regulation of MRP4 (ABCC4)
10.20-10.40 Coffee break
11.40-11.20 Peter Chiba, Institute of Medical Chemistry, Medical University of Vienna: Two for one: C2 rotational pseudosymmetry effects a dual binding mode for P-glycoprotein substrates
11.20-12.00 Saibal Dey, Department of Biochemistry and Molecular Biology, Uniformed Services University School of Medicine, Bethesda, MD: Mechanism of stereospecific sensing by a polyspecific drug transporter
Wednesday, September 4 Poster session 13.00-15.00
Wednesday, September 4 afternoon session
15.00-15.40 Scott Moye-Rowley, Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA: Regulation of membrane composition by ABC transporters
15.40-16.20 William Douglas Figg, Center for Cancer Research, National Cancer Institute, Bethesda, MD: Don't forget about the OATPs: They move drugs also
16.20-16.40 Coffee break
16.40-17.20 Frances J. Sharom, Department of Molecular and Cellular Biology, University of Guelph, ON: Drug binding and transport by P-glycoprotein (ABCB1)
17.20-18.00 Tamas Aranyi, Inserm U 951, Université d'Evry Val d'Essonne: Transcriptional regulation of human ABC transporters: the example of ABCC6
Thursday, September 5 Morning session
9.00-9.40 Andre Goffeau, Catholic University of Louvain-la-Neuve: The fungal multidrug transporters
9.40-10.20 Tito Fojo, Center for Cancer Research, National Cancer Institute, Bethesda, MD, Title to be announced
10.20-10.40 Coffee break
10.40-11.20 Murray Norris, Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, University of New South Wales:Clinical and physiological roles of ABCC transporters in cancer: more than just drug efflux pumps
11.20-12.00 Gergely Szakacs, Institute of Enzymology, Hungarian Academy of Sciences: MDR- Engage, Evade of Exploit?
Thursday, September 5 Poster session 13.00-15.00
Thursday, September 5 afternoon session
15.00-15.40 Brian Day, Department of Medicine, National Jewish Health, Denver, CO: Harnessing glutathione transport as a therapeutic approach to treat disease
15.40-16.20 Attilio Di Pietro, Institut de Biologie et Chimie des Protéines, Lyon: Different strategies using drug-efflux inhibitors and apoptosis inducers to target multidrug resistant cancer cells overexpressing ABC transporters
16.20-16.40 Coffee break
16.40-17.20 Jorg Koenig, Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-University Erlangen-Nuremberg: Multiple-transfected cell models for the analysis of the apically localized export pumps MRP2 and P-gp
17.20-18.00 Georg Sager, Department Medical Pharmacology and Toxicology,University of Tromso: ABC-transporters and clinical pharmacology
Friday, September 6 Morning session
9.00-9.40 Jean-Michel Scherrmann, INSERM, U705 ; CNRS UMR 8206, Universités Paris Descartes et Diderot, Paris: Pharmacokinetic-pharmacodynamic relationships between ABC transporters and psychoactive xenobiotics
9.40-10.20 Anika Hartz, College of Pharmacy, University of Minnesota, Duluth, MN: P-glycoprotein at the Blood-Brain Barrier and the Alzheimer’s disease enigma
10.20-11.00 Coffee break
11.00-11.40 András Váradi, Institute of Enzymology, Hungarian Academy of Sciences: Experimental strategies for in vivo rescue of disease-causing mutants of ABCC6
11.40-12.20 Grzegorz Bartosz, University of Łódź: Scenes from the ABCC family album
12.20-13.15 Toshihisa Ishikawa, Omics Science Center, RIKEN Yokohama Institute: New challenges in human ABC transporters research: From bench to clinical practice
testoplek
Ministry of Regional Development
University of Lodz
Ministry of Science and Higher Education